I tried a grass and weed killer, but it hasn't phased it. Pick the berries, make a mellow wine, drink said wine becoming even more mellow yourself. Plus loving touches and soft humming poems to get them in the mood. Good products include triclopyr and glyphosate, that can be found at a local gardening store. If the bush begins to grow back, try using herbicides as an option. Make sure to follow the directions exactly to get the best benefits. Place some bleach in a spray bottle and spray on the weed you wish to remove. In fact, a simple bleach and detergent solution is all you need to start the removal process. Spraying too early usually leads to poor control and regrowth of plants. You don’t need too many things, but still, make sure that you have the following. Where blackberry plants are encroaching and need to be controlled, they should be sprayed only after the plants have bloomed and good soil moisture is present. Keep an eye on the area where the blackberry bush was. Again, bleach will kill anything but if you do get some on a plant you want to keep, just wash the plant off. We cut the tree down to the ground just 3 weeks ago and this is how fast the blackberries have grown back. It isn’t easy to remove blackberry bushes once they are established, but it can be done with perseverance and patience. High strength bleach: for a small tree or plant, even domestic bleach can work, but for a large tree stump, you will need heavy-duty bleach. Then mechanically till the area. Hardiness Zone: 7b. Immediately after you've cut down for the last time, dig the bushes out, doing your very best to dig out as much of the root system as you can. Remove any roots you see. While vines can provide a wonderful ground cover in your yard, they also can quickly get out of hand and choke out nearby plants and shrubs. This bush is growing out of a tree stump that we can't get to. The best way to kill blackberries is to cause them to over produce massive full ripe fat berries with plenty of fertilizer, water and just the right shade / sun mixture. Blackberry brambles have a tendency to go a little loco: wild blackberries can regenerate from the crown or rhizomes even after herculean efforts are taken to destroy the plants. Removing the vines is not a difficult process, however. By Cricket from Parkton, NC Answers: Getting Rid of Blackberry Bushes The bleach chemicals will evaporate or dissipate in about two days (or less but better safe than sorry), making the area safe for planting. It’s recognisable for its long, thorny shoots and for producing succulent blackberries, and while these tasty fruits make a great pie or jam, the bramble plant itself is considered a nuisance in most gardens. It's spreading into the lawn. Brambles, commonly known as a blackberry bush, is a perennial bush that grows throughout the country. 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